Mike Loizzi

Principal Global Investors LLC, dba Principal Asset Management (Principal AM), is a SEC-registered investment advisor headquartered in Des Moines, Iowa. The firm was founded in 1998 and is a wholly owned subsidiary of the Principal Global Investors Holding Co. (US) LLC and their ultimate parent is Principal Financial Group, Inc. (NASDAQ: PFG). Principal AM provides investment advisory services to institutional investors and individuals on a discretionary or non-discretionary basis.

U.S. Bank NA (Cincinnati Ohio Investment Management) (USB-IM) is the investment management division of U.S. Bank NA, a commercial bank headquartered in Minneapolis, Minnesota. The firm is ultimately held by the US Bancorp (NYSE: USB). USB-IM provides tailored investment management services to individuals and institutional investors.

National Merit Scholarship Corp. conducts academic scholarship competition for recognition and university scholarships. The company was founded in 1995 and is headquartered in Evanston, IL.

Digi-Key Corp. distributes electronic components. It also distributes semiconductors, discrete, electromechanical parts. Its products include audio products, batteries, cable assemblies, capacitors, computer & video accessories, connectors, crystals & oscillators, discrete semiconductor products and many more. The company was founded by Ronald A. Stordahl in 1972 and is headquartered in Thief River Falls, MN.

Prilenia Therapeutics BV develops and manufactures pharmaceuticals. The company was founded in 2018 and is headquartered in Naarden, the Netherlands.

GreenLight Biosciences, Inc. engages in a biotechnology company.. It delivers attractive solution for production of chemicals and fuels from renewable resources, eliminating the need for petroleum feedstocks. The company was founded by Andrey J. Zarur, Marta Ortega-Valle, and James R. Swartz and is headquartered in Medford, MA.

Alentis Therapeutics AG develops novel medications to treat advanced liver diseases and cancers. The company was founded by Neil Goldsmith on March 1, 2019 and is headquartered in Basel, Switzerland.

Part of NewAmsterdam Pharma Co. NV, NewAmsterdam Pharma Holding BV is a Dutch company that engages in research and development of transformative therapies for cardio metabolic diseases. The company is based in Naarden, the Netherlands. The company was founded in 2019 by John Jacob Pieter Kastelein. Michael H. Davidson has been the CEO of the company since 2020. NewAmsterdam Pharma Holding was acquired by Frazier Lifesciences Acquisition Corp. on November 22, 2022 for $468.74 million.

Apic Bio, Inc. engages in the development of treatment for neurological and liver diseases. It offers THRIVE, a platform that silences a mutant gene product and replaces a normal gene product in a single dual function vector. The company was founded by Robert H. Brown, Jr., John Reilly, and Christian Mueller in 2017 and is headquartered in North Cambridge, MA.

Inotrem SA specializes in the development of therapeutic approaches based on its proprietary TREM-1 platform. The firm focuses on the control of immune reactions in acute inflammatory diseases. The company was founded by Jean-Jacques Garaud, Marc Derive and Sebastien Gibot in 2013 and is headquartered in Paris, France.

Foley & Lardner LLP engages in the provision of legal services. Its practice areas include employee benefits and executive compensation, environmental, estates and trusts, finance, international tax and transfer pricing, private equity and venture capital, real estate, securities, commodities and exchange regulation, taxation, and transactions. The company was founded by Asahel Finch and William Pitt Lynde on September 8, 1842 and is headquartered in Milwaukee, WI.

Allysta Pharmaceuticals, Inc. operates as a biopharmaceutical company. The frim develops medicine for ophthalmology, particularly dry eye disease and glaucoma. The company was founded by Henry H. Hsu and is headquartered in San Mateo, CA.

NewAmsterdam Pharma BV develops novel drugs to treat dyslipidemia. It operates as a biotechnology company and develops anti-dyslipidemic compounds in cardiovascular disease indications. The firm's product DEZ-001 develops a potent cholesteryl ester transfer protein inhibitor that has shown a decrease of low-density lipoprotein levels, and an increase of high-density lipoprotein levels. The company was founded by John J. P. Kastelein in 2012 and is headquartered in Naarden, the Netherlands.

Morningside Group (Morningside Group) is a venture capital and private equity firm founded in 1986 by Lok Chung Chan and Chi Chung Chan. The firm is headquartered in Hong Kong.

Zielbio, Inc. develops a technology for identification of cancerous diseases. Its technology identifies high-value biomarkers of disease as well as companion targeting peptides capable of delivery of therapeutic payloads and as imaging agents. The company was founded by Kimberly A. Kelly, Gregory B. Fralish, Todd William Bauer in 2010 and is headquartered in Charlottesville, VA.

Alms Therapeutics SAS provides research and development in the treatment of diabetes. The company was founded by Jason Robert Dinges on July 4, 2017 and is headquartered in Paris, France.

Adiso Therapeutics, Inc. creates medicines to treat inflammatory diseases with the goal of improving the lives of patients and their families. Adiso Therapeutics is based in Concord, MA. The company believes that current therapeutic approaches are often inadequate and can pose significant safety concerns for patients. Scott T. Megaffin has been the CEO of the company since 2022.

Winefest Des Moines operates as a three-day festival that is held in June of each year. It hosts notable national and international vintners and wine imports, and pairs the world’s wines with innovative culinary creations from guest chefs. The company was founded in 2003 and is headquartered in Des Moines, IA.

BrokerTech Ventures LLC (BrokerTech Ventures) is a venture capital firm founded in 2019 by Daniel T. Keough and Mike Victorson. The firm is headquartered in Des Moines, Iowa.

Holmes, Murphy & Associates LLC provides risk management and insurance brokerage services. It specializes in agriculture, health and human services, and specialty benefits. The company was founded by Max L. Holmes in 1932 and is headquartered in Waukee, IA.

Metropolitan Life Insurance Co. (Investment Portfolio) (MetLife-IM) is the insurance management division of Metropolitan Life Insurance Co., which is owned by MetLife, Inc. (NYSE: MET), a global provider of insurance, annuities and employee benefit programs. The firm is headquartered in New York City with additional office in Morristown, New Jersey. MetLife-IM offers group dental benefit plans for individuals, employees, retirees and their families and provides dental plan administration for over 20 million people. The firm provides disability products for individuals, as well as employee and association groups who receive them through their employer.

Access Ventures, Inc (Access Ventures) is a venture capital firm founded in 2014 by Bryce Butler. The firm is headquartered in Louisville, Kentucky.

Vilcap Advisory LLC (Vilcap Advisory) is a venture capital firm subsidiary of Vilcap Inc founded in 2009 by Victoria Elouise Fram and Ross E Baird. The firm is headquartered in Washington, DC.

Federal Home Loan Bank of Des Moines engages in the provision of collateralized loans. Its products and services include overnight advances, fixed rate advances, variable rate advances, callable advances, and community investment advances. The company was founded on October 31, 1932 and is headquartered in Des Moines, IA.

Pinteon Therapeutics, Inc. develops cancer and CNS therapeutics. It focuses on the discovery and development of therapeutics targeting Pin1. The firm specializes in aberrant disease processes and improves patient outcomes in medical need indications. The company is headquartered in Newton Centre, MA.

Canterra Capital Corp. engages in the provision of farmland management services. It offers asset and property management, administrative and other services in the agriculture sector. The company is headquartered in Regina, Canada.

Part of ELL Environmental Holdings Ltd., Greatcorp International Ltd. functions as an investment holding Chinese company. The company is based in Hong Kong, Hong Kong.

BTC Capital Management, Inc. (BTC Capital) is a registered investment advisor headquartered in Des Moines, Iowa. The firm was founded in 2003 and is owned by BTC Financial Corp. BTC Capital provides discretionary investment management services, non-discretionary investment management services, and advisory/consulting services to their clients both directly and as a sub-advisor on behalf of other entities. Their clients include individuals, trusts, retirement plans, businesses, government entities, foundations, endowments, investment companies, private funds and other institutional clients.

Bankers Trust Co. is an asset management headquartered in Des Moines, Iowa. The firm was founded in 1917 and is a subsidiary of BTC Financial Corp. The firm serves as a trusted partner for individuals’ comprehensive financial planning, trust and fiduciary needs.

Agfunder, Inc. (Agfunder) is a venture capital firm founded in 2012 by Rob Leclerc, Michael Dean, Melissa Tilney and Justin Bruch. The firm is headquartered in San Francisco, California.

Clear Frontier Ag Management LLC acquires and develops farmlands. The company was founded by Justin Bruch in 2019 and is headquartered in Omaha, NE.

CellCentric Ltd. develops and commercializes small molecule inhibitors for cancer. Its active programs include inhibitors to histone methyltransferases, histone demethylases and epigenetic enzymes that act via ubiquitin. The company was founded by Alun Huw Jones, Catherine Denise Prescott, Azim Surani and William Henry Lewarne West in May 2004 and is headquartered in Cambridge, the United Kingdom.