Marc Appel

Asalyxa Bio, Inc. is a drug development and platform technology company that focuses on developing novel therapeutics to treat major unmet medical needs caused by the dysregulation of immune signaling. The company is based in Southfield, MI. The company's platform technology enables the delivery of existing and novel drugs directly into over-reactive immune cells, with applications across a wide array of disease areas and conditions. The company was founded by Marc Appel, who has been the CEO since incorporation.

IpiNovyx Bio, Inc. is a drug development and platform technology company that focuses on developing novel therapeutics to treat autoimmune and inflammatory diseases through selective inhibition of the immunoproteasome. The company is based in West Nyack, NY. The company's platform technology enables highly selective, reversible, and non-toxic inhibition of various immune cell types, with applications across a range of indications with underlying immunopathology. Orange Grove Bio (OGB) is an emerging, preclinical, capital allocation, and asset development biotech company that partners with universities and entrepreneurs to develop innovative treatments for important diseases, particularly cancer and immune disorders. The company was founded by Jim Graham, and the CEO is Marc Appel.

Orange Grove Bio LLC is a preclinical biotech company that partners with universities and entrepreneurs to develop innovative treatments for important diseases, particularly cancer and immune disorders. The company is based in Cincinnati, OH. The company fosters strong relationships with entrepreneurs and technology transfer offices outside of the traditional medical technology hubs. Orange Grove Bio's team possesses more than one hundred years of drug development and company creation experience, allowing it to build and finance innovative programs from the research and development stage to clinical trials. The company was founded by Marc Appel. Marc Appel has been the CEO since incorporation.