Kevan Shokat

5AM Venture Management LLC (5AM Ventures) is an Independent Venture Capital firm founded in 2002 by Andrew J. Schwab, Carin M. Rollins and John D. Diekman. The firm is headquartered in San Francisco, US.

eFFECTOR Therapeutics Operations, Inc. discovers and develops translation regulators. It offers small molecule therapeutics that control gene expression for the treatment of cancer and other serious diseases. Its pipeline of translation regulators includes eFT508, eIF4E, and eIF4A. The company was founded by James R. Appleman, Kevin L. Eastwood, Siegfried Reich, Davide Ruggero, Kevan Shokat, and Stephen T. Worland in 2012 and is headquartered in San Diego, CA.

Intellikine LLC develops and manufactures small molecule drugs for the treatment of cancer. The company focused on the development of potent, selective small molecule inhibitors of the PI3K/Akt/mTOR pathway for the treatment of cancer, inflammation and autoimmune disorders. Intellikine was founded on May 2nd, 2007 and is headquartered in La Jolla, CA.

Mitokinin, Inc. develops kinase neo-substrates for the treatment of neurodegenerative and mitochondrial diseases. The company was founded by Kevan Shokat, Nicholas Hertz, and Daniel de Roulet Jr. and is headquartered in New York, NY.

Rezo Therapeutics, Inc. is a drug discovery company based in San Francisco, CA. The company's mission is to revolutionize traditional drug development by integrating proteomics, genetics, structural biology, chemistry, artificial intelligence, and machine learning to create maps of molecular disease networks. Rezo's initial focus is on oncology, but they plan to explore additional therapeutic areas through collaborations and partnerships. The company was founded by Natalia Jura, Kevan Shokat, Nevan Krogan, Sourav Bandyopadhyay, Norbert W. Bischofberger, and George A. Scangos, with Nevan Krogan serving as CEO since incorporation.