Mary Fernandes

Immunophotonics, Inc. develops proprietary novel drug product for use in a minimally invasive therapeutic cancer vaccine. Its vaccine process under development, inCVAX, is a two injection procedure into one or more selected tumors: The first injection is a needle with an optical fiber (coupled to a laser) that heats selected tumor(s) locally; The second injection is experimental drug product, a proprietary synthesized carbohydrate polymer, that is intended to recruit and activate antigen-presenting cells, potentially triggering a cascade that leads to a systemic anti-tumor immune response. The company was founded by Lu Alleruzzo and Tomas Hode in 2009 and is headquartered in St. Louis, MI.

Kypha, Inc. engages in the development of devices and products to monitor and treat inflammatory and autoimmune disorders. Its products include Comp act, RapiPlex, and sample stabilization. The company was founded by Paul K. Olson and Chad M. Stiening on January 14, 2011 and is headquartered in St. Louis, MO.

Euclises Pharmaceuticals, Inc. operates as a biopharmaceutical company. The firm develops a portfolio of COX-2 inhibitors optimized for cancer treatment based on its proprietary Euclicoxib platform and is in the process of selecting a lead clinical development candidate. The company was founded by John J. Talley in 2011 and is headquartered in St. Louis, MO.

Aclaris Life Sciences, Inc. operates as a technology-based company which focuses on rational drug design to identify novel drugs for cancer and chronic inflammatory diseases. It also engages in design and development of kinase inhibitors that target key enzymes involved in the regulation of cancer growth, survival and metastasis in modulations of chronic inflammation. The company was founded by Joseph B. Monahan, Gabriel Mbalaviele and Shaun R. Selness in 2010 and is headquartered in St. Louis, MO.

Apse, Inc. offers technology and strategy services. It develops technology that will allow the cost efficient production of RNA for broad acre topical RNAi uses in agriculture. The company was founded by Juan Arhancet in 2011 and is headquartered in St. Louis, MO.

Prostate Management Diagnostics, Inc. engages in the provision of research and test of fluid-based screening tool to identify patients at risk of prostate cancer. It performs research on a series of genetic markers that could determine whether a prostrate cancer is indolent or aggressive in patients newly diagnosed with the disease. The company was founded by Christopher B. Ehrlich and Douglas C. Fisher in 2014 and is headquartered in Sausalito, CA.

Part of Incyte Corp., Genome Systems, Inc. is a company that researches and develops biotechnical products. The company is based in St. Louis, MO. The company was founded by David Adam Smoller. Genome Systems was acquired by Incyte Corp. on July 23, 1996 for $7.33 million.

Thompson Street Capital Managers LLC (Thompson Street Capital) is a private equity subsidiary of Thompson Street Capital Partners LLC, founded in 2000 by James A. Cooper and Peter Finley. The firm is headquartered in St. Louis, Missouri.

D3 Technologies, Inc. provides engineering services. It offers commercial and military aviation, military weapons systems, structural design and analysis capability, and program management. The company is headquartered in San Diego, CA.

BioGenerator (Venture Capital) (BioGenerator) is a venture capital subsidiary of BioGenerator founded in 2003. The firm is headquartered in St. Louis, Missouri.

Adarza BioSystems, Inc. develops and manufacturers a multiplex immunoassay technology that can identify proteins and genetic markers in medical specimens. The firm operates as a medical diagnostics company which also develops a rapid and label-free biological assay platform for measuring clinical and point-of-care samples and also its technology allows hundreds of tests to be run simultaneously on a single chip. The company was founded by Benjamin L. Miller, Randolph R. Henke, Terry Gronwall and Christopher C. Striemer in 2008 and is headquartered in St. Louis, MO.

Vector Laboratories, Inc. develops, manufactures and markets labeling and detection reagents for immunohistochemistry, immunofluorescence, DNA/RNA and glycobiology. Its products include neuronal tracers, ultrapure immunological products, and novel reagents for detection and isolation of nucleic acids, fusion proteins and carbohydrates. The company was founded in 1976 and is headquartered in Burlingame, CA.

Sigma-Aldrich Co. is a privately held life science and technology company. They produce chemical and biochemical products and kits for scientific research. The company was founded in 1934 and is headquartered in Saint Louis, MO

Arch Oncology, Inc. develops drugs for life-threatening disorders. Its products include anti-CD47 monoclonal antibody, CD47 antisense oligonucleotide, and a small molecule CD47 inhibitor. The company was founded by William A. Frazier and Jeffrey S. Isenberg in 2006 and is headquartered in Brisbane, CA.

Cultivation Capital LLC (Cultivation Capital) is a venture capital firm founded in 2012 by Brian Matthews, Cliff Holekamp, Jim McKelvey, Kyle Welborn, and Peter Esparrago. The firm is headquartered in St. Louis, Missouri.

Sequoia Vaccines, Inc. is a clinical stage pharmaceutical company engages in developing vaccine to prevent recurrent urinary tract infections and small molecules treating cancers and bacterial infections. The company was founded by Gary Eldridge in 2012 and is headquartered in St. Louis, MO.

Part of Revvity, Inc., Sage Labs, Inc. is a company that provides animal research models and support services. The company is based in St. Louis, MO. Sage Labs was acquired by Horizon Discovery Group Ltd., part of Revvity, Inc. from December 24, 2020 on September 29, 2014 for $48.05 million.

CoverCress, Inc. operates as a renewable fuel company. It develops and commercializes field pennycress as an oilseed crop that is used to produces oil for industrial and renewable fuels, and meal for nutritious livestock feed. The company was founded by Vijay Chauhan, Dennis M. Plummer and Mike Roth and is headquartered in St. Louis, MO.

Part of KVC Behavioral Healthcare Missouri, Inc., Great Circle is a company that provides behavioral health services. The company is based in St. Louis, MO. The company was founded in 2009. The CEO is Paula Fleming. Great Circle was acquired by KVC Behavioral Healthcare Missouri, Inc. on April 01, 2023.

Elira, Inc. develops a system to suppress appetite and assist diet adherence. The company was founded by John Faul in 2015 and is headquartered in St. Louis, MO.

Edison Agrosciences, Inc. provides agricultural biotechnology services. The firm specializes in agriculture, biotechnology and rubber. The company was founded by Matthew B. Crisp and Thomas M. Hohn and is headquartered in Creve Coeur, MO.

Unleash Immuno Oncolytics, Inc. develops oncolytic virus immunotherapy products to treat cancer. Its product is UIO-512. the company is headquartered in Saint Louis, MO.

Canopy Biosciences LLC engages in the provision of products and services for gene editing, gene expression analysis and regulation, and bioprocessing. It offers crispr complete kits, mirna crispr knockout kits, clia certified services, compbio, mirna mimics, and cho complete. The company was founded by David Adam Smoller, Edward J. Weinstein and Crystal Winkeler in 2016 and is headquartered in St. Louis, MO.

Plastomics operates as biotechnology company, which develops chloroplast genetic for next generation of high performing crops. The company was founded by Ralph Bock and Jeff Staub in 2016 and is headquartered in St. Louis, MO.

Disguise Technologies Ltd. provides business support services. It specializes in design, sequence, control. The company is headquartered in London, the United Kingdom.

Cadre Bioscience LLC develops novel therapeutics for human diseases. The company was founded by Charlie Bolten and is headquartered in Saint Louis, MO.

Real Estate Connected LLC engages in the provision of real estate technology and transactions coordination software solutions for agents and coordinators. The company was founded by Bryan Bowles in 2017 and is headquartered in St. Charles, MO.

Impetus Agriculture, LLC is an American company that specializes in growing commercial biotech crops and developing bio pesticide formulations. The company was founded in 2018, and Martha Schlicher has been the CEO of the company since 2020.

Hermann Cos., Inc. (Hermann Co) is a private equity and venture capital firm founded in 1956. The firm is headquartered in St. Louis, Missouri.

Hypha Life Sciences LLC operates as a research services company providing biotechnology innovators access to premium R&D capabilities in genetic engineering and metabolomics. The company is based in Wilmington, DE. The company was founded by Charles Bolten and Tom Cohen. The CEO is Tom Cohen.

Lewis & Clark AgriFood (Lewis & Clark AgriFood) is a venture capital firm founded in 2016. The firm headquartered in Saint Louis, Missouri.

MediBeacon, Inc. provides optical diagnostic products and services. It offers Optical Renal Function Monitor, a platform focused on kidney function monitoring in real-time at the point-of-care. The company was founded by Steven J. Hanley and Richard B. Dorshow in 2012 and is headquartered in St. Louis, MO.